Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775291 | 0.84 | NAAA (0.38) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL14002948 | 0.83 | ACE (0.53) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775205 | 0.82 | ACE (0.44) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9773200 | 0.80 | ACE (0.66) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9773234 | 0.80 | CHRM2 (0.36) | ACEMEN1KMT2ACYP3A4EPHX2 | |
| SCHEMBL15825448 | 0.80 | ACE (0.39) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775313 | 0.79 | HCAR2 (0.44) | ACEEPHX2CHRM2CHRM4CHRM5 | |
| SCHEMBL9775317 | 0.79 | HCAR2 (0.44) | ACEEPHX2CHRM2CHRM4CHRM5 | |
| SCHEMBL9775259 | 0.78 | ACE (0.51) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775315 | 0.78 | HCAR2 (0.37) | ACEMEN1KMT2ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999370-A | ANXIOLYTIC AGENTS, INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME, NOOTROPIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |