Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775281 | 0.85 | ALDH1A1 (0.46) | ACECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9773234 | 0.84 | CHRM2 (0.36) | ACEEPHX2PREPCHRM2CHRM4 | |
| SCHEMBL9775457 | 0.84 | ACE (0.43) | ACEEPHX2CHRM2CHRM4CHRM5 | |
| SCHEMBL15825448 | 0.84 | ACE (0.39) | ACEEPHX2PREPCHRM2CHRM4 | |
| SCHEMBL9775317 | 0.83 | HCAR2 (0.44) | NAAAACEEPHX2CHRM2CHRM4 | |
| SCHEMBL9775313 | 0.83 | HCAR2 (0.44) | NAAAACEEPHX2CHRM2CHRM4 | |
| SCHEMBL9775268 | 0.81 | FKBP1A (0.47) | ACECYP3A4ALOX15MEN1KMT2A | |
| SCHEMBL9775321 | 0.81 | HCAR2 (0.37) | NAAAACEEPHX2CHRM2CHRM4 | |
| SCHEMBL9775315 | 0.81 | HCAR2 (0.37) | NAAAACEEPHX2CHRM2CHRM4 | |
| SCHEMBL4798155 | 0.81 | ACE (0.41) | ACEPREPCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068242-A | PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AND THEIR USE FOR PSYCHOTROPIC ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |