Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.45 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775627 | 0.85 | XPO1 (0.48) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9775626 | 0.83 | RAB9A (0.49) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL11200852 | 0.81 | NPC1 (0.51) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL9775656 | 0.77 | NPC1 (0.51) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL9775653 | 0.75 | MEN1 (0.46) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL11370104 | 0.75 | NPC1 (0.50) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL9775581 | 0.74 | NPC1 (0.48) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL9775604 | 0.72 | RAB9A (0.49) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL9775636 | 0.71 | SMN1; SMN2 (0.55) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL9775616 | 0.71 | RAB9A (0.50) | RAB9ANPC1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987140-A | ANTIINFLAMMATORY, ANTIRHEUMATIC | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | claimed |
| US-4987140-A | ANTIINFLAMMATORY, ANTIRHEUMATIC | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | disclosed |
| US-4925859-A | Novel 4-hydroxy-3-pyridine-carboxamides useful for treating inflammation and rheumatism | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |