Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31030969 | 0.91 | TTR (0.60) | NPSR1TTRDPP4CA12CA1 | |
| SCHEMBL1177761 | 0.91 | TTR (0.60) | NPSR1TTRDPP4CA12CA1 | |
| SCHEMBL1177764 | 0.91 | TTR (0.60) | NPSR1TTRDPP4CA12CA1 | |
| Hydrochloric Acid SCHEMBL10463631 | 0.90 | TTR (0.58) | NPSR1TTRDPP4CA12CA1 | |
| Hydrochloric Acid SCHEMBL10463632 | 0.90 | TTR (0.58) | NPSR1TTRDPP4CA12CA1 | |
| SCHEMBL4427602 | 0.81 | TTR (0.69) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL4427604 | 0.81 | TTR (0.69) | TTRDPP4CA12CA1CA2 | |
| SCHEMBL19637918 | 0.80 | APP (0.62) | NPSR1TTRDPP4BACE1PKM | |
| SCHEMBL1578505 | 0.78 | KDM4E (0.64) | NPSR1TTRDPP4CA12CA1 | |
| SCHEMBL1578506 | 0.78 | KDM4E (0.64) | NPSR1TTRDPP4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987140-A | ANTIINFLAMMATORY, ANTIRHEUMATIC | ROUSSEL UCLAF (FR) | 1991-01-22 | — | — | US | disclosed |
| US-4925859-A | Novel 4-hydroxy-3-pyridine-carboxamides useful for treating inflammation and rheumatism | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |