SCHEMBL9775755

SCHEMBL9775755

C=C(C)c1ccc(OC(=O)OC(C)([Si](C)(C)C)[Si](C)(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 12/20 0.53
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.37
MAPT P10636 3/20 0.37
HSD17B10 Q99714 1/20 0.36
KDM1A O60341 1/20 0.35
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GLA P06280 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9775778 0.87 ELANE (0.56) ELANEKMT2ALMNAMAPTHPGD
SCHEMBL653574 0.85 ELANE (0.72) ELANEKMT2AMEN1LMNAMAPT
SCHEMBL9740987 0.81 KMT2A (0.53) ELANEKMT2AMEN1LMNAMAPT
SCHEMBL23842601 0.75 ELANE (0.56) ELANEKMT2AMEN1MAPTHSD17B10
SCHEMBL4060714 0.75 ELANE (0.77) ELANEKMT2AMEN1LMNAMAPT
SCHEMBL7061315 0.74 ELANE (0.46) ELANEKMT2AMEN1LMNAMAPT
SCHEMBL1088052 0.74 LMNA (0.65) ELANEKMT2AMEN1LMNAMAPT
SCHEMBL25695941 0.74 ELANE (0.55) ELANEMAPTKDM1ATDP1L3MBTL1
SCHEMBL23842564 0.73 ELANE (0.49) ELANEKMT2AMEN1MAPTHSD17B10
SCHEMBL8983109 0.72 KMT2A (0.46) ELANEKMT2AMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4916247-A INTERMEDIATES FOR POLYMERS SUITABLE FOR PHOTORESISTS; OXYGEN RESISTANT CIBA-GEIGY CORPORATION (US) 1990-04-10 US claimed
EP-0307356-A2 Organometallic compounds CIBA-GEIGY AG (CH) 1989-03-15 EP claimed
US-5024916-A Dry developable photoresist CIBA-GEIGY CORPORATION (US) 1991-06-18 US disclosed
US-4965316-A ORGANOMETALLIC CONTAINING POLYMERS CIBA-GEIGY CORPORATION (US) 1990-10-23 US disclosed
US-4916247-A INTERMEDIATES FOR POLYMERS SUITABLE FOR PHOTORESISTS; OXYGEN RESISTANT CIBA-GEIGY CORPORATION (US) 1990-04-10 US disclosed
EP-0307353-A2 Organometal-containing polymers and their use CIBA-GEIGY AG (CH) 1989-03-15 EP disclosed
EP-0307356-A2 Organometallic compounds CIBA-GEIGY AG (CH) 1989-03-15 EP disclosed