Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775891 | 0.93 | MIF (0.41) | MIFTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL29980061 | 0.82 | KEAP1 (0.51) | MIFTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL1389163 | 0.82 | KEAP1 (0.51) | MIFTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL9786138 | 0.82 | KEAP1 (0.41) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL13004014 | 0.81 | MIF (0.41) | MIFTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL9775889 | 0.81 | MIF (0.40) | MIFTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL4714980 | 0.79 | TDP1 (0.42) | MIFTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL19971534 | 0.79 | MIF (0.43) | MIFTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL30680417 | 0.79 | ALDH1A1 (0.42) | MIFTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL30297970 | 0.79 | MIF (0.43) | MIFTSHRALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053509-A | Microbiocides; AIDS | LABORATOIRE ROGER BELLON (FR) | 1991-10-01 | — | — | US | disclosed |
| US-5004745-A | Benzo[1,8]naphthyridine derivatives, their preparation and the compositions which contain them | LABORATOIRE ROGER BELLON (FR) | 1991-04-02 | — | — | US | disclosed |
| US-4990515-A | Chemical intermediates | RHONE-POULENC SANTE (FR) | 1991-02-05 | — | — | US | disclosed |
| US-4970213-A | Benzo(1,8)naphthyridine derivatives as intermediates | RHONE-POULENC SANTE (FR) | 1990-11-13 | — | — | US | disclosed |