Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109663 | 0.92 | HTT (0.58) | HTTALDH1A1TDP1TSHRHCAR3 | |
| SCHEMBL29392416 | 0.89 | ALDH1A1 (0.68) | ALDH1A1TDP1TSHRHCAR3MAPT | |
| SCHEMBL127370 | 0.89 | ALDH1A1 (0.68) | ALDH1A1TDP1TSHRHCAR3MAPT | |
| SCHEMBL10536086 | 0.88 | ALDH1A1 (0.59) | HTTALDH1A1TDP1TSHRHCAR3 | |
| SCHEMBL11780708 | 0.88 | HTT (0.64) | HTTALDH1A1TDP1TSHRHCAR3 | |
| SCHEMBL9776282 | 0.87 | HCAR3 (0.58) | HTTALDH1A1TDP1TSHRHCAR3 | |
| SCHEMBL11773204 | 0.87 | HTT (0.58) | HTTALDH1A1TDP1HCAR3MAPT | |
| SCHEMBL2467529 | 0.85 | HTT (0.57) | HTTALDH1A1HCAR3MAPTKMT2A | |
| SCHEMBL7239404 | 0.85 | ALDH1A1 (0.56) | HTTALDH1A1TDP1TSHRHCAR3 | |
| SCHEMBL5713544 | 0.85 | ALDH1A1 (0.56) | HTTALDH1A1TDP1TSHRHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041143-A | N,N'-disubstituted nitro-para-phenylenediamines, and dyeing compositions containing the same | L'OREAL (FR) | 1991-08-20 | — | — | US | disclosed |
| US-4910341-A | Reacting chloroethyl chloroformate with 4-halo-3-nitroaniline in presence of a base; cyclization; alkaline hydrolysis | L'OREAL (FR) | 1990-03-20 | — | — | US | disclosed |
| US-4904276-A | Nitroaminophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate nitroaminobenzenes and their use in dyeing keratinous fibres | L'OREAL (FR) | 1990-02-27 | — | — | US | disclosed |
| US-4863481-A | HAIR DYES | L'OREAL (FR) | 1989-09-05 | — | — | US | disclosed |
| US-4749379-A | HAIR DYES | L'OREAL (FR) | 1988-06-07 | — | — | US | disclosed |
| US-4740622-A | 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols | L'OREAL (FR) | 1988-04-26 | — | — | US | disclosed |