Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748805 | 0.94 | ALDH1A1 (0.58) | HCAR3ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL127370 | 0.91 | ALDH1A1 (0.68) | HCAR3ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL29392416 | 0.91 | ALDH1A1 (0.68) | HCAR3ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL9776301 | 0.87 | HTT (0.61) | HCAR3ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL7031913 | 0.86 | ALDH1A1 (0.61) | HCAR3ALDH1A1TSHRTDP1PKM | |
| SCHEMBL8645124 | 0.86 | ALDH1A1 (0.61) | HCAR3ALDH1A1TSHRTDP1PKM | |
| SCHEMBL11772321 | 0.85 | HCAR3 (0.57) | HCAR3ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL7095920 | 0.84 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1LMNAPKM | |
| SCHEMBL19666254 | 0.84 | ALDH1A1 (0.54) | HCAR3ALDH1A1TSHRTDP1LMNA | |
| SCHEMBL7239404 | 0.84 | ALDH1A1 (0.56) | HCAR3ALDH1A1TSHRTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041143-A | N,N'-disubstituted nitro-para-phenylenediamines, and dyeing compositions containing the same | L'OREAL (FR) | 1991-08-20 | — | — | US | disclosed |
| US-4910341-A | Reacting chloroethyl chloroformate with 4-halo-3-nitroaniline in presence of a base; cyclization; alkaline hydrolysis | L'OREAL (FR) | 1990-03-20 | — | — | US | disclosed |