Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7300872 | 0.93 | HSD17B10 (0.44) | HSD17B10MBTPS1MAPK1CTSLCTSB | |
| SCHEMBL10948828 | 0.83 | TACR1 (0.51) | MAPK1CTSLCTSBCTSSTYR | |
| SCHEMBL11028843 | 0.83 | TACR1 (0.55) | HSD17B10MBTPS1MAPK1CTSLCTSB | |
| SCHEMBL25471899 | 0.82 | MBTPS1 (0.49) | MBTPS1MAPK1CTSLCTSBCTSS | |
| SCHEMBL7298898 | 0.80 | MAPT (0.42) | EGFRTACR1TP53 | |
| Ammonia Solution, Strong SCHEMBL7302333 | 0.80 | MME (0.43) | HSD17B10CTSLCTSBCTSSTYR | |
| Ammonia Solution, Strong SCHEMBL7425286 | 0.78 | CAPN1 (0.51) | CTSLCTSBCTSSCTSK | |
| SCHEMBL9777172 | 0.77 | CAPN1 (0.52) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7296176 | 0.77 | TYR (0.55) | CTSLCTSBCTSSTYRMEN1 | |
| SCHEMBL27406872 | 0.77 | TYR (0.55) | CTSLCTSBCTSSTYRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073547-A | DOPAMINE PRO-DRUG | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1991-12-17 | — | — | US | disclosed |