Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9777157 | 0.93 | HSD17B10 (0.44) | HSD17B10MBTPS1MAPK1CTSLCTSB | |
| Ammonia Solution, Strong SCHEMBL7302333 | 0.87 | MME (0.43) | HSD17B10CTSLCTSBCTSSTYR | |
| Ammonia Solution, Strong SCHEMBL7425286 | 0.85 | CAPN1 (0.51) | CTSLCTSBCTSSCTSK | |
| SCHEMBL9777172 | 0.84 | CAPN1 (0.52) | CTSLCTSBCTSSCTSK | |
| SCHEMBL17693623 | 0.83 | KYNU (0.53) | CTSLCTSBCTSSTYRMEN1 | |
| SCHEMBL10948828 | 0.83 | TACR1 (0.51) | MAPK1CTSLCTSBCTSSTYR | |
| SCHEMBL11028843 | 0.83 | TACR1 (0.55) | HSD17B10MBTPS1MAPK1CTSLCTSB | |
| SCHEMBL7302573 | 0.80 | MAPT (0.42) | TACR1TP53 | |
| SCHEMBL7294519 | 0.77 | GRB2 (0.46) | — | |
| SCHEMBL7296176 | 0.77 | TYR (0.55) | CTSLCTSBCTSSTYRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393781-B1 | Dopamine pro-drug | ZAMBON SPA (IT) | 1995-02-08 | — | — | EP | disclosed |
| US-5073547-A | DOPAMINE PRO-DRUG | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1991-12-17 | — | — | US | disclosed |