Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777411 | 1.00 | ATIC (0.53) | ATICALDH1A1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL14413251 | 0.88 | SUMO2 (0.60) | ATICALDH1A1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL3714723 | 0.84 | ATIC (0.52) | ATICALDH1A1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL3714721 | 0.84 | ATIC (0.52) | ATICALDH1A1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL3487054 | 0.78 | CTRB1 (0.64) | ATICALDH1A1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL9640919 | 0.78 | APP (0.81) | ALDH1A1CYP1A2MEN1APPMAPT | |
| SCHEMBL9639508 | 0.78 | APP (0.81) | ALDH1A1CYP1A2MEN1APPMAPT | |
| SCHEMBL27752545 | 0.77 | CTRB1 (0.63) | ATICALDH1A1CYP1A2CYP2C9ALOX15 | |
| SCHEMBL9777406 | 0.76 | APP (0.55) | ATICALDH1A1CYP1A2HIF1AMEN1 | |
| SCHEMBL9777410 | 0.76 | APP (0.55) | ATICALDH1A1CYP1A2HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039511-A | Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-5008099-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-04-16 | — | — | US | disclosed |
| US-4933156-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0287909-A1 | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1988-10-26 | — | — | EP | disclosed |