Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SLC7A11 | Q9UPY5 | 5/20 | 0.55 |
| ▸ | SENP2 | Q9HC62 | 7/20 | 0.54 |
| ▸ | SENP1 | Q9P0U3 | 7/20 | 0.54 |
| ▸ | SUMO2 | P61956 | 5/20 | 0.54 |
| ▸ | SUMO1 | P63165 | 5/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.54 |
| ▸ | SENP3 | Q9H4L4 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777410 | 1.00 | APP (0.55) | APPMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL23787540 | 0.90 | APP (0.68) | APPMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL9639508 | 0.82 | APP (0.81) | APPMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL9640919 | 0.82 | APP (0.81) | APPMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL23787784 | 0.82 | SENP2 (0.71) | APPMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL23787680 | 0.80 | SENP2 (0.54) | APPMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL2856243 | 0.78 | CYP2D6 (0.57) | APPMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL26964487 | 0.77 | SENP2 (0.56) | APPMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL23787684 | 0.77 | ALDH1A1 (0.45) | APPMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL23787634 | 0.77 | ALDH1A1 (0.56) | APPMEN1ALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039511-A | Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-5008099-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-04-16 | — | — | US | disclosed |
| US-4933156-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0287909-A1 | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1988-10-26 | — | — | EP | disclosed |