Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166708 | 0.80 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL5574954 | 0.77 | TSHR (0.67) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL11324371 | 0.71 | MEN1 (0.55) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL11778968 | 0.71 | MEN1 (0.55) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL3346423 | 0.71 | MEN1 (0.55) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL6171 | 0.71 | TSHR (0.77) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL4067863 | 0.71 | TSHR (0.77) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL9058372 | 0.71 | TSHR (0.77) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Triethylene Glycol SCHEMBL7858578 | 0.69 | MEN1 (0.69) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL392786 | 0.69 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000866-A | Antifreeze compositions containing alkane tetracarboxylic acid for use with hard water | FIRST BRANDS CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0217340-B1 | CARBOXY-SUBSTITUTED ORGANOSILICON STABILIZERS FOR A SILICATE-CONTAINING ANTIFREEZE | UNION CARBIDE CORPORATION (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4822901-A | Carboxy-substituted organosilicon stabilizers for a silicate-containing antifreeze | UNION CARBIDE CORPORATION (US) | 1989-04-18 | — | — | US | disclosed |
| US-4772408-A | CORROSION RESISTANCE, GELATION INHIBITION | FIRST BRANDS CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4767599-A | Silicate-containing antifreeze with carboxy-substituted organosilicon stabilizer | FIRST BRANDS CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| US-4725405-A | Organosiloxane-silicate copolymer antifreeze composition with nitrate corrosion inhibitor | FIRST BRANDS CORPORATION (US) | 1988-02-16 | — | — | US | disclosed |
| US-4701277-A | Silicate-containing antifreeze with carboxy-substituted organosilicon stabilizer | FIRST BRANDS CORPORATION (US) | 1987-10-20 | — | — | US | disclosed |
| US-4684475-A | Organophosphate and silicate containing antifreeze | FIRST BRANDS CORPORATION (US) | 1987-08-04 | — | — | US | disclosed |
| US-4676919-A | Low pH-buffered silicon/silicate antifreeze concentrates | FIRST BRANDS CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| US-4664833-A | AUTOMOBILE COOLANTS | UNION CARBIDE CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0217340-A2 | Carboxy-substituted organosilicon stabilizers for a silicate-containing antifreeze | UNION CARBIDE CORPORATION (US) | 1987-04-08 | — | — | EP | disclosed |