Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778072 | 0.86 | PPARD (0.57) | ALDH1A1CA12CA9MAPK1L3MBTL1 | |
| SCHEMBL10591514 | 0.85 | MAPK1 (0.47) | ALDH1A1CA12CA9MAPK1AKR1B1 | |
| SCHEMBL9773949 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CA12CA9MAPK1TSHR | |
| SCHEMBL9777967 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPK1GAAKMT2AMEN1 | |
| SCHEMBL29236538 | 0.82 | RPS6KA2 (0.52) | ALDH1A1MAPK1LMNAKMT2AMEN1 | |
| SCHEMBL29236539 | 0.82 | RPS6KA2 (0.52) | ALDH1A1MAPK1LMNAKMT2AMEN1 | |
| SCHEMBL10593868 | 0.81 | CA12 (0.44) | ALDH1A1CA12CA9MAPK1AKR1B1 | |
| SCHEMBL29236536 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1LMNATSHRKMT2A | |
| SCHEMBL29236534 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1LMNATSHRKMT2A | |
| SCHEMBL29236529 | 0.79 | CASP3 (0.53) | ALDH1A1MAPK1TSHRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |