Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778019 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL10594053 | 0.82 | CASP3 (0.43) | CA9MAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9778058 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTTNF | |
| SCHEMBL9777977 | 0.81 | ALDH1A1 (0.49) | CA12CA9MAPK1ALDH1A1KMT2A | |
| SCHEMBL10591053 | 0.76 | RPS6KA2 (0.54) | MAPK1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9778045 | 0.76 | SLC7A5 (0.43) | MAPK1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9777967 | 0.74 | ALDH1A1 (0.47) | MAPK1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9778090 | 0.74 | HSD17B10 (0.56) | MAPK1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL17497373 | 0.71 | MAPK1 (0.48) | CA12CA9MAPK1ALDH1A1KMT2A | |
| SCHEMBL9880857 | 0.70 | RPS6KA2 (0.50) | ALDH1A1KMT2AMEN1HPGDCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |