Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997700 | 0.80 | HTT (0.56) | ALOX5CYP1A2HTTTSHRALDH1A1 | |
| SCHEMBL6075636 | 0.80 | HTT (0.57) | ALOX5ALOX15CYP1A2HTTTSHR | |
| SCHEMBL9778175 | 0.79 | HPGD (0.55) | ALOX15CYP1A2ALDH1A1L3MBTL1POLB | |
| SCHEMBL6751131 | 0.78 | ALOX5 (0.49) | ALOX5CYP1A2HTTTSHRNLRP3 | |
| SCHEMBL822462 | 0.78 | NAAA (0.59) | ALOX5ALOX15HTTTSHRALDH1A1 | |
| SCHEMBL54245 | 0.78 | NAAA (0.59) | ALOX5ALOX15HTTTSHRALDH1A1 | |
| SCHEMBL17361219 | 0.78 | NAAA (0.59) | ALOX5ALOX15HTTTSHRALDH1A1 | |
| SCHEMBL5056873 | 0.78 | NAAA (0.59) | ALOX5ALOX15HTTTSHRALDH1A1 | |
| SCHEMBL6075731 | 0.78 | HTT (0.64) | ALOX5ALOX15CYP1A2HTTTSHR | |
| SCHEMBL30875601 | 0.75 | TSHR (0.51) | ALOX5ALOX15HTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5009934-A | Process for preparing poly-(imidesiloxanes) | WACKER-CHEMIE GMBH (DE) | 1991-04-23 | — | — | US | disclosed |