Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16939921 | 0.92 | HSD17B10 (0.51) | HSD17B10RAB9ANPC1TAAR1GAA | |
| SCHEMBL13409453 | 0.91 | ALDH1A1 (0.56) | HSD17B10RAB9ANPC1TAAR1GAA | |
| SCHEMBL13055389 | 0.87 | TAAR1 (0.60) | HSD17B10RAB9ANPC1TAAR1GAA | |
| SCHEMBL1416169 | 0.83 | HSD17B10 (0.58) | HSD17B10RAB9ANPC1TAAR1GAA | |
| SCHEMBL21925516 | 0.83 | HSD17B10 (0.54) | HSD17B10RAB9ANPC1TAAR1GAA | |
| SCHEMBL1833771 | 0.83 | HSD17B10 (0.58) | HSD17B10RAB9ANPC1TAAR1GAA | |
| SCHEMBL18389610 | 0.83 | — | — | |
| SCHEMBL9276339 | 0.83 | TAAR1 (0.57) | RAB9ANPC1TAAR1GAA | |
| SCHEMBL126140 | 0.83 | HSD17B10 (0.54) | HSD17B10RAB9ANPC1TAAR1GAA | |
| SCHEMBL11584841 | 0.83 | HSD17B10 (0.54) | HSD17B10RAB9ANPC1TAAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110546135-B | Method for producing isocyanate | 旭化成株式会社 | 2021-12-14 | — | — | CN | disclosed |
| CN-110546135-A | Method for producing isocyanate | ASAHI CHEMICAL IND | 2019-12-06 | — | — | CN | disclosed |
| US-20170298169-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2017-10-19 | — | — | US | disclosed |
| US-20150210631-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-07-30 | — | — | US | disclosed |
| US-5068391-A | Rearrangement of bis/N-carboalkoxyanilino/methane in the presence of hydrofluoric acid | RHONE-POULENC CHIMIE (FR) | 1991-11-26 | — | — | US | disclosed |
| US-5066827-A | From ethyl N-phenylcarbamate and formaldehyde, trioxane, methylal or paraformaldehyde, hydrofluoric acid catalyst, intermediate for diphenylmethane diisocyanate | RHONE-POULENC CHIMIE (FR) | 1991-11-19 | — | — | US | disclosed |
| EP-0410900-A1 | Method for the preparation of methylene di(phenylurethane) | RHONE-POULENC CHIMIE (FR) | 1991-01-30 | — | — | EP | disclosed |
| EP-0406129-A1 | Method for the preparation of methylene di(phenylurethane) | RHONE-POULENC CHIMIE (FR) | 1991-01-02 | — | — | EP | disclosed |
| US-4307029-A | Process for preparing polymethylene-polyphenyl polyisocyanates | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1981-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298169-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | TST, SUDS3, SCLY | HSD17B10 592/4885RAB9A 4633/4885NPC1 2034/4885 |
| US-20150210631-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | TST, SUDS3, SCLY | HSD17B10 592/4885RAB9A 4633/4885NPC1 2034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.