Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778560 | 0.94 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778662 | 0.93 | MAPT (0.48) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778888 | 0.92 | APP (0.55) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778946 | 0.92 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778863 | 0.88 | KDM4E (0.47) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778660 | 0.86 | APP (0.53) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778530 | 0.86 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778622 | 0.80 | MAOB (0.59) | MAOBMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL4370495 | 0.77 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL9778629 | 0.75 | SIGMAR1 (0.41) | SLC6A4HTR2CHTR2BMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063197-A | Aromatic compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-11-05 | — | — | US | disclosed |