Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778777 | 0.93 | DRD2 (0.43) | KDM4EDRD2DRD4DRD3KCNH2 | |
| SCHEMBL9778800 | 0.90 | KCNH2 (0.44) | KDM4EDRD2DRD4DRD3KCNH2 | |
| SCHEMBL9779134 | 0.87 | KDM4E (0.45) | KDM4EKCNH2HRH3SMN1; SMN2 | |
| SCHEMBL9778708 | 0.86 | SMN1; SMN2 (0.45) | KDM4EL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9778775 | 0.86 | HRH3 (0.50) | HRH3SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9778909 | 0.86 | L3MBTL1 (0.47) | KDM4EDRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL9778602 | 0.85 | MAOB (0.47) | KCNH2HRH3ALDH1A1 | |
| SCHEMBL9778740 | 0.85 | DRD2 (0.43) | KDM4EDRD2DRD4DRD3KCNH2 | |
| SCHEMBL3083609 | 0.84 | RAB9A (0.44) | MEN1KMT2ACYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL9778840 | 0.84 | MAOB (0.49) | DRD2DRD3KCNH2HRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063197-A | Aromatic compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-11-05 | — | — | US | disclosed |