Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778709 | 0.84 | MAPT (0.52) | MAPTLMNAKDM4EALDH1A1TSHR | |
| SCHEMBL9778765 | 0.84 | ALDH1A1 (0.45) | MAPTTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL9778572 | 0.83 | DRD2 (0.49) | MAPTTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL9778537 | 0.78 | L3MBTL1 (0.47) | MAPTTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL31336657 | 0.78 | POLB (0.54) | MAPTPOLBTDP1LMNAALDH1A1 | |
| SCHEMBL9778940 | 0.76 | MAPT (0.52) | MAPTTDP1LMNAKDM4EALDH1A1 | |
| SCHEMBL9778755 | 0.76 | MAOB (0.53) | MAPTLMNAKDM4EALDH1A1AR | |
| SCHEMBL9778699 | 0.76 | MAPT (0.60) | MAPTLMNAKDM4EALDH1A1DRD2 | |
| SCHEMBL9778416 | 0.75 | MAPT (0.48) | MAPTPOLBTDP1LMNAKDM4E | |
| SCHEMBL9778647 | 0.73 | ALDH1A1 (0.47) | MAPTPOLBLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063197-A | Aromatic compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-11-05 | — | — | US | disclosed |