Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778467 | 0.94 | LMNA (0.49) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL9778840 | 0.86 | MAOB (0.49) | DRD2HRH3KCNH2MAOB | |
| SCHEMBL9778602 | 0.84 | MAOB (0.47) | HTTHRH3KCNH2MAOBTAAR1 | |
| SCHEMBL9778909 | 0.84 | L3MBTL1 (0.47) | MAPK1SMN1; SMN2DRD2DRD4KDM4E | |
| SCHEMBL9778856 | 0.81 | KCNA3 (0.48) | HTTHRH3KCNH2MAOBTAAR1 | |
| SCHEMBL9778641 | 0.80 | MAOB (0.48) | HTTSMN1; SMN2TP53TSHRMAOB | |
| SCHEMBL9778597 | 0.79 | MAOB (0.51) | DRD2HRH3KCNH2MAOB | |
| SCHEMBL9778546 | 0.79 | LMNA (0.45) | LMNAMAPK1HTTSMN1; SMN2DRD2 | |
| SCHEMBL9778740 | 0.78 | DRD2 (0.43) | MAPK1HTTSMN1; SMN2DRD2DRD4 | |
| SCHEMBL9778747 | 0.78 | MAOB (0.50) | MAOBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063197-A | Aromatic compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 1991-11-05 | — | — | US | disclosed |