Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6518295 | 0.89 | KDM4E (0.64) | KDM4EALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL9779094 | 0.83 | ALDH1A1 (0.67) | KDM4EALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL5567460 | 0.82 | KDM4E (1.00) | KDM4EALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL29580772 | 0.79 | KDM4E (0.78) | KDM4EALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL42002 | 0.79 | KDM4E (0.78) | KDM4EALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL30148368 | 0.78 | KDM4E (0.76) | KDM4EALDH1A1RAB9AHPGDLMNA | |
| Hydrochloric Acid SCHEMBL16115604 | 0.77 | KDM4E (0.76) | KDM4EALDH1A1RAB9AHPGDLMNA | |
| Hydrochloric Acid SCHEMBL9036642 | 0.77 | KDM4E (0.76) | KDM4EALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL22939217 | 0.76 | ALDH1A1 (0.63) | KDM4EALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL6739125 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1RAB9AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999369-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-03-12 | — | — | US | disclosed |
| US-4910218-A | With a hydroxy containing secondary amine group | BURROUGHS WELLCOME CO. (US) | 1990-03-20 | — | — | US | disclosed |