Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 6/20 | 0.53 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780732 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL5622542 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7954222 | 0.85 | ALOX15 (0.57) | KDM4EALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL19332451 | 0.85 | ALOX15 (0.57) | KDM4EALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL17429439 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL3606511 | 0.84 | RAB9A (0.50) | KDM4EALDH1A1RAB9AHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL13684586 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL2015917 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL701020 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7325236 | 0.81 | ALDH1A1 (0.56) | KDM4EALDH1A1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | BIGNON ERIC (FR) | 2004-03-04 | — | — | US | disclosed |
| CN-1263528-A | N-triazolyl-2-indolecarboxamides and their use in CCK-A agonists | SANOFI SYNTHELABO (FR) | 2000-08-16 | — | — | CN | disclosed |
| US-4060626-A | Indole-carboxylic carbon compounds and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1977-11-29 | — | — | US | disclosed |
| US-3996241-A | 2-Hydroxymethyl indole compounds and blood sugar lowering compositions | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043995-A1 | Novel triazole derivatives, process for their preparation and pharmaceutical compositions containing them | CCKAR, CCKBR, NPY1R | KDM4E 1971/4885ALDH1A1 2097/4885RAB9A 1127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.