Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769958 | 0.87 | SMN1; SMN2 (0.37) | KMT2ANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL9327532 | 0.80 | TDP1 (0.38) | KMT2ANPC1RAB9AMEN1TDP1 | |
| Hydrochloric Acid SCHEMBL9326182 | 0.78 | TDP1 (0.37) | KMT2ANPC1RAB9AMEN1TDP1 | |
| SCHEMBL3841166 | 0.76 | TDP1 (0.44) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9779593 | 0.72 | PKM (0.41) | KMT2ANPC1SMN1; SMN2MEN1TDP1 | |
| SCHEMBL13603867 | 0.72 | BCHE (0.39) | KMT2AMEN1CYP1A2POLBALDH1A1 | |
| SCHEMBL13603849 | 0.72 | KMT2A (0.39) | KMT2ARAB9ASMN1; SMN2MEN1TDP1 | |
| SCHEMBL4841869 | 0.72 | MEN1 (0.52) | KMT2ATP53SMN1; SMN2MEN1TDP1 | |
| SCHEMBL13603869 | 0.71 | TDP1 (0.39) | KMT2ASMN1; SMN2TDP1POLBALDH1A1 | |
| SCHEMBL6557201 | 0.71 | CHRM2 (0.39) | KMT2ANPC1RAB9AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015659-A | Cognition activators to slow aging of the brain | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |