Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779358 | 0.87 | KMT2A (0.38) | SMN1; SMN2NPC1RAB9ATP53POLB | |
| SCHEMBL9779593 | 0.86 | PKM (0.41) | SMN1; SMN2NPC1POLBKMT2AMEN1 | |
| SCHEMBL9327532 | 0.81 | TDP1 (0.38) | NPC1RAB9APOLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9326182 | 0.80 | TDP1 (0.37) | NPC1RAB9APOLBKMT2AMEN1 | |
| SCHEMBL8760992 | 0.75 | SLC6A2 (0.39) | SMN1; SMN2NPC1RAB9APOLBKMT2A | |
| SCHEMBL8388974 | 0.69 | POLB (0.37) | SMN1; SMN2NPC1RAB9APOLBKMT2A | |
| SCHEMBL7563803 | 0.67 | TDP1 (0.47) | SMN1; SMN2POLBKMT2AALDH1A1TSHR | |
| SCHEMBL11057975 | 0.66 | TSHR (0.43) | SMN1; SMN2NPC1RAB9ATP53KMT2A | |
| SCHEMBL9850025 | 0.65 | ALOX5 (0.46) | SMN1; SMN2NPC1RAB9APOLBKMT2A | |
| SCHEMBL8627738 | 0.65 | POLB (0.46) | NPC1RAB9APOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987134-A | DISORDERS OF BRAIN FUNCTIONS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |