Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769958 | 0.86 | SMN1; SMN2 (0.37) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL9327532 | 0.79 | TDP1 (0.38) | ALDH1A1POLBMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9326182 | 0.78 | TDP1 (0.37) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL9779358 | 0.72 | KMT2A (0.38) | ALDH1A1MAPTGAASMN1; SMN2POLB | |
| SCHEMBL8760992 | 0.72 | SLC6A2 (0.39) | PKMALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL1556688 | 0.72 | ALDH1A1 (0.40) | PKMALDH1A1MAPTGAAKEAP1 | |
| SCHEMBL8388974 | 0.70 | POLB (0.37) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL18055614 | 0.69 | TDP1 (0.53) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL21788947 | 0.68 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL10666068 | 0.68 | KMT2A (0.42) | ALDH1A1MAPTGAASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015659-A | Cognition activators to slow aging of the brain | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |