Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779169 | 0.86 | ALDH1A1 (0.60) | GAAMAPTKDM4EHTTMEN1 | |
| SCHEMBL9779162 | 0.81 | AGTR1 (0.57) | GAAMAPTKDM4EHTTMEN1 | |
| Isonicotinoylhydrazone Of Acetophenone SCHEMBL6637701 | 0.79 | GAA (0.76) | GAAMAPTCYP3A4KDM4EMEN1 | |
| Isonicotinoylhydrazone Of Acetophenone SCHEMBL6637694 | 0.79 | GAA (0.76) | GAAMAPTCYP3A4KDM4EMEN1 | |
| SCHEMBL6687709 | 0.79 | GAA (0.66) | GAAMAPTCYP3A4KDM4EHTT | |
| SCHEMBL14413395 | 0.79 | GAA (0.66) | GAAMAPTCYP3A4KDM4EHTT | |
| SCHEMBL1514859 | 0.76 | POLB (0.68) | GAAMAPTCYP3A4KDM4EHTT | |
| SCHEMBL1514861 | 0.76 | POLB (0.68) | GAAMAPTCYP3A4KDM4EHTT | |
| SCHEMBL2996962 | 0.75 | GAA (0.54) | GAAMAPTCYP3A4KDM4EKMT2A | |
| SCHEMBL2998191 | 0.74 | GAA (0.56) | GAAMAPTCYP3A4KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066695-A | Plastics; heat resistance, dispersibility | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0349489-A2 | Organic macromolecular material containing a hydrazone-based metal complex pigment | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |