Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.65 |
| ▸ | BCHE | P06276 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | TYK2 | P29597 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.53 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413395 | 1.00 | GAA (0.66) | GAAPOLBAGTR1BCHEMAPT | |
| SCHEMBL1562723 | 0.89 | GSTA1 (0.68) | POLBAGTR1BCHEMAPTRAB9A | |
| SCHEMBL9768852 | 0.88 | BCHE (0.67) | GAAPOLBAGTR1BCHEMAPT | |
| Isonicotinoylhydrazone Of Acetophenone SCHEMBL6637701 | 0.83 | GAA (0.76) | GAAPOLBMAPTRAB9AKDM4E | |
| SCHEMBL1514859 | 0.83 | POLB (0.68) | GAAPOLBAGTR1MAPTRAB9A | |
| SCHEMBL1514861 | 0.83 | POLB (0.68) | GAAPOLBAGTR1MAPTRAB9A | |
| Isonicotinoylhydrazone Of Acetophenone SCHEMBL6637694 | 0.83 | GAA (0.76) | GAAPOLBMAPTRAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL10805629 | 0.82 | ALDH1A1 (0.62) | GAAPOLBAGTR1BCHEMAPT | |
| SCHEMBL1025581 | 0.81 | AGTR1 (0.76) | GAAPOLBAGTR1MAPTRAB9A | |
| SCHEMBL9768851 | 0.80 | GAA (0.76) | GAAPOLBMAPTRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580403-A2 | APYRASE INHIBITORS | Texas Crop Science, Inc. (US) | 2025-07-09 | — | — | EP | claimed |
| US-20240101510-A1 | APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | claimed |
| WO-2024050040-A2 | APYRASE INHIBITORS | TEXAS CROP SCIENCE (US) | 2024-03-07 | — | — | WO | claimed |
| US-20240101510-A1 | APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
| WO-2004076640-A2 | SMALL-MOLECULE INHIBITORS OF ANGIOGENIN AND RNASES AND IN VIVO AND IN VITRO METHODS OF USING SAME | AMBION, INC. (US) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101510-A1 | APYRASE INHIBITORS | APEH, DPEP1, PON1 | GAA 168/4885POLB 3494/4885AGTR1 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.