Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376800 | 0.85 | ABCC9 (0.38) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9779699 | 0.82 | ABCC9 (0.37) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9779684 | 0.82 | ABCC9 (0.37) | ABCC9MALT1ABCB1CASP3 | |
| SCHEMBL9779700 | 0.82 | ABCC9 (0.37) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7275951 | 0.81 | PDE4A (0.41) | ABCC9TDP2ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8085371 | 0.81 | TDP2 (0.37) | ABCC9TDP2ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9376009 | 0.80 | ABCC9 (0.37) | ABCC9TDP2ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9373199 | 0.79 | ABCC9 (0.36) | ABCC9MALT1ABCB1CASP3 | |
| SCHEMBL9374699 | 0.77 | ABCC9 (0.37) | ABCC9MALT1ABCB1CASP3 | |
| SCHEMBL9779788 | 0.77 | ABCC9 (0.43) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036068-A | Cardiovascular disorders | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-07-30 | — | — | US | disclosed |
| EP-0371312-A1 | Benzoxazine derivatives | MERCK PATENT GmbH (DE) | 1990-06-06 | — | — | EP | disclosed |