Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634632 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL13358883 | 0.72 | KIF11 (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL1482504 | 0.72 | TDP2 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8129086 | 0.70 | MEN1 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9779703 | 0.70 | MAOA (0.36) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL30912172 | 0.70 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL18582934 | 0.70 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5016641 | 0.70 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5058433 | 0.70 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2720506 | 0.70 | ALDH1A1 (0.70) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256981-B1 | TITANOCENES AND THEIR USE | CIBA-GEIGY AG (CH) | 1993-02-17 | — | — | EP | disclosed |
| US-4963470-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| EP-0186626-B1 | TITANOCENES AND COMPOSITIONS CURABLE BY IRRADIATION CONTAINING THESE TITANOCENES | CIBA-GEIGY AG (CH) | 1988-09-14 | — | — | EP | disclosed |
| EP-0256981-A2 | Titanocenes and their use | CIBA-GEIGY AG (CH) | 1988-02-24 | — | — | EP | disclosed |
| US-4713401-A | PHOTOINITIATORS ORTHO-CF2Z GROUP | CIBA SPECIALTY CHEMICALS CORPORATION | 1987-12-15 | — | — | US | disclosed |
| EP-0186626-A2 | Titanocenes and compositions curable by irradiation containing these titanocenes | CIBA-GEIGY AG (CH) | 1986-07-02 | — | — | EP | disclosed |