Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342097 | 0.82 | MAPT (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20322974 | 0.79 | HTR3E (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9780057 | 0.79 | MTNR1A (0.44) | PARP1ALDH1A1SMN1; SMN2RXRARXRB | |
| SCHEMBL9779969 | 0.79 | SCN2A (0.39) | RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9779999 | 0.79 | ALDH1A1 (0.46) | PARP1ALDH1A1HTTRAB9APTGIR | |
| SCHEMBL9780014 | 0.79 | PARP1 (0.42) | PARP1ALDH1A1PTGIRPTGDRKMT2A | |
| SCHEMBL680475 | 0.79 | NPSR1 (0.44) | ALDH1A1HTTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL13644972 | 0.79 | MAPT (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1120687 | 0.79 | MAPT (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9133587 | 0.78 | ALDH1A1 (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0340030-A2 | Triazine derivatives | GLAXO GROUP LIMITED (GB) | 1989-11-02 | — | — | EP | disclosed |