Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 3/20 | 0.55 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795688 | 0.90 | MEN1 (0.50) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL5873117 | 0.90 | LMNA (0.50) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL28795608 | 0.87 | CES2 (0.48) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL28795622 | 0.87 | CES2 (0.48) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL28945734 | 0.87 | LMNA (0.46) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL11056951 | 0.87 | CES2 (0.48) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL11618685 | 0.86 | TDP1 (0.52) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL5873120 | 0.84 | ALDH1A1 (0.52) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL9157900 | 0.84 | ALDH1A1 (0.64) | TDP1L3MBTL1CES2CES1LMNA | |
| SCHEMBL9157738 | 0.84 | TDP1 (0.56) | TDP1L3MBTL1CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741621-A | PHOTORESISTS, SOLDER MASKS, PRINTING PLATES, PROOFING FILM PRODUCTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-21 | — | — | US | claimed |
| EP-0747769-A2 | Process for producing photoimageable films prepared from aqueous photoimageable liquid emulsions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-12-11 | — | — | EP | claimed |
| CN-114805044-A | Novel method for synthesizing dibromo compound | 兰州大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-103739465-A | Synthesis method of 1, 3-diphenyl-2-bromo-2-propene-1-one | ANHUI RUISAI BIOCHEMICAL TECHNOLOGY CO LTD | 2014-04-23 | — | — | CN | disclosed |
| US-7951827-B2 | Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-05-31 | — | — | US | disclosed |
| US-7872029-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | BOWEN J PHILLIP | 2011-01-18 | — | — | US | disclosed |
| US-20090018167-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Robinson, Thomas Philip (US) | 2009-01-15 | — | — | US | disclosed |
| EP-1058697-B1 | POLYMERIC FILMS HAVING CONTROLLED VISCOSITY RESPONSE TO TEMPERATURE AND SHEAR | DU PONT (US) | 2008-11-26 | — | — | EP | disclosed |
| US-7432303-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Bowen, J. Phillip (US) | 2008-10-07 | — | — | US | disclosed |
| CN-100350327-C | Process for continuous liquid processing of photosensitive compositions having reduced levels of residues | DU PONT (US) | 2007-11-21 | — | — | CN | disclosed |
| EP-1093020-B1 | Wound storage roll of composite photosensitive element | DU PONT (US) | 2007-04-04 | — | — | EP | disclosed |
| EP-1058697-A1 | POLYMERIC FILMS HAVING CONTROLLED VISCOSITY RESPONSE TO TEMPERATURE AND SHEAR | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-12-13 | — | — | EP | disclosed |
| WO-1999046644-A1 | PROCESS FOR THE CONTINUOUS LIQUID PROCESSING OF PHOTOSENSITIVE COMPOSITIONS HAVING REDUCED LEVELS OF RESIDUES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-09-16 | — | — | WO | disclosed |
| WO-1999045045-A1 | POLYMERIC FILMS HAVING CONTROLLED VISCOSITY RESPONSE TO TEMPERATURE AND SHEAR | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-09-10 | — | — | WO | disclosed |
| EP-0889363-A1 | Near IR sensitive photoimageable/photopolymerizable compositions, media, and associated processes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-07 | — | — | EP | disclosed |
| EP-0666504-B1 | Aqueous photoimageable liquid emulsion, photoimageable film and process of manufacture | DU PONT (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5741621-A | PHOTORESISTS, SOLDER MASKS, PRINTING PLATES, PROOFING FILM PRODUCTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0747769-A2 | Process for producing photoimageable films prepared from aqueous photoimageable liquid emulsions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |
| EP-0666504-A1 | Aqueous photoimageable liquid emulsion, photoimageable film and process of manufacture | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5407783-A | Thermostability, shelf life | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018167-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | FLT1, FLT4, VEGFA | TDP1 4435/4885L3MBTL1 4205/4885CES2 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.