SCHEMBL9780402

SCHEMBL9780402

N#Cc1ncn([C@@H]2O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]2O)n1

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ATG7 O95352 19/20 0.58
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA4 P22748 1/20 0.51
CA9 Q16790 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12151512 0.83 ADORA3 (0.44) ATG7
SCHEMBL24024488 0.83 LMNA (0.69) ATG7CA1CA2CA4CA9
SCHEMBL7572340 0.83 LMNA (0.69) ATG7CA1CA2CA4CA9
SCHEMBL9780396 0.82 ATG7 (0.56) ATG7CA1CA2CA4CA9
SCHEMBL13352081 0.81 LMNA (0.59)
SCHEMBL13320587 0.81 LMNA (0.59)
SCHEMBL9780439 0.81 LMNA (0.59)
SCHEMBL6917119 0.81 LMNA (0.42) ATG7
SCHEMBL12150458 0.80 LMNA (0.45) ATG7
SCHEMBL12300351 0.78 LMNA (0.44) ATG7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4992426-A Antiparasitic 5'-sulfamoyl nucleosides NUCLEIC ACID RESEARCH INSTITUTE (US) 1991-02-12 US claimed
US-4992426-A Antiparasitic 5'-sulfamoyl nucleosides NUCLEIC ACID RESEARCH INSTITUTE (US) 1991-02-12 US disclosed
US-4992426-A Antiparasitic 5'-sulfamoyl nucleosides NUCLEIC ACID RESEARCH INSTITUTE (US) 1991-02-12 US disclosed