Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780778 | 0.95 | KMT2A (0.62) | KMT2APYGLAKR1B1HPGDL3MBTL1 | |
| SCHEMBL9780857 | 0.93 | KMT2A (0.61) | KMT2APYGLAKR1B1HPGDL3MBTL1 | |
| SCHEMBL9780958 | 0.91 | KMT2A (0.67) | KMT2APYGLAKR1B1L3MBTL1MEN1 | |
| SCHEMBL9501831 | 0.89 | POLB (0.56) | KMT2ARAB9AHPGDL3MBTL1FFAR4 | |
| SCHEMBL27634252 | 0.82 | KMT2A (0.49) | KMT2APYGL | |
| SCHEMBL4788971 | 0.81 | TSHR (0.55) | KMT2ARAB9AL3MBTL1FFAR4MEN1 | |
| SCHEMBL3161189 | 0.80 | MEN1 (0.58) | KMT2ARAB9AHPGDL3MBTL1FFAR4 | |
| SCHEMBL3729436 | 0.79 | KMT2A (1.00) | KMT2AAKR1B1HPGD | |
| SCHEMBL27654735 | 0.78 | MAPT (0.45) | KMT2APYGLRAB9AL3MBTL1MEN1 | |
| SCHEMBL11230817 | 0.77 | KMT2A (0.46) | KMT2ARAB9AAKR1B1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010060-A | Method of treating herpes simplex viral infection employing pyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4851519-A | AMIDO NUCLEOSIDES, VIRICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-07-25 | — | — | US | disclosed |