Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL11385707 | 0.83 | KMT2A (0.55) | ESR1ESR2MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL24808008 | 0.83 | TSHR (0.62) | ESR1ESR2MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9629832 | 0.82 | PTPN11 (0.46) | RXRARXRBRXRGEGFRGAA | |
| SCHEMBL28123080 | 0.81 | RXRA (0.57) | RXRARXRBRXRGESR1ESR2 | |
| SCHEMBL150516 | 0.81 | KMT2A (0.61) | RXRARXRBRXRGESR1ESR2 | |
| SCHEMBL30098854 | 0.80 | EGFR (0.45) | RXRARXRBRXRGKMT2AEGFR | |
| SCHEMBL2039468 | 0.80 | CA12 (0.62) | KMT2AEGFRTTRALDH1A1TSHR | |
| SCHEMBL28096375 | 0.80 | ESR1 (0.73) | ESR1ESR2MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29473817 | 0.80 | CA12 (0.62) | KMT2AEGFRTTRALDH1A1TSHR | |
| SCHEMBL7085249 | 0.79 | MAPT (0.62) | RXRARXRBRXRGESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988460-A | HYDROGEN BONDED ADDITION POLYMERS, POLYCARBONATES, POLYESTERS, OR POLYAMIDES, AROMATIC ESTER DERIVATIVES AS LIQUID CRYSTALS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-01-29 | — | — | US | disclosed |