Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695041 | 0.82 | GCGR (0.42) | PTGS2GCGRKMT2APTGS1THRB | |
| SCHEMBL9697138 | 0.76 | KMT2A (0.34) | ALDH1A1PTGS2GCGRKMT2APTGS1 | |
| SCHEMBL9695099 | 0.73 | PTGS2 (0.39) | ALDH1A1PTGS2KMT2APTGS1HTR1A | |
| SCHEMBL9696155 | 0.72 | KMT2A (0.35) | ALDH1A1PTGS2GCGRKMT2APTGS1 | |
| SCHEMBL9696143 | 0.71 | KMT2A (0.53) | ALDH1A1PTGS2KMT2APTGS1KCNK3 | |
| SCHEMBL9696224 | 0.69 | HMGCR (0.38) | THRB | |
| SCHEMBL9696231 | 0.68 | HMGCR (0.37) | THRB | |
| SCHEMBL6477047 | 0.59 | PTGS2 (0.43) | ALDH1A1SMN1; SMN2PTGS2KMT2APTGS1 | |
| SCHEMBL6291378 | 0.59 | RIPK3 (0.44) | KMT2A | |
| SCHEMBL9696229 | 0.58 | KMT2A (0.43) | ALDH1A1PTGS2GCGRKMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025000-A | Anticholesterol, antilipemic agents | E. R. SQUIBB & SONS, INC. (US) | 1991-06-18 | — | — | US | disclosed |