Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PROC | P04070 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781024 | 0.88 | HTR1A (0.37) | HTR1AHTR1DHTR2CTSHRMEN1 | |
| SCHEMBL28038484 | 0.83 | CHEK1 (0.42) | HTR1AHTR1DHTR2CTSHRMEN1 | |
| SCHEMBL29027761 | 0.83 | CYP4F2 (0.37) | HTR1AHTR1DHTR2CTSHRMEN1 | |
| SCHEMBL28080162 | 0.82 | MEN1 (0.45) | TSHRMEN1KMT2ASLC6A3KDM4E | |
| SCHEMBL27804389 | 0.82 | MEN1 (0.45) | TSHRMEN1KMT2ASLC6A3KDM4E | |
| SCHEMBL27699889 | 0.82 | MEN1 (0.45) | TSHRMEN1KMT2ASLC6A3KDM4E | |
| SCHEMBL29290752 | 0.82 | MEN1 (0.45) | TSHRMEN1KMT2ASLC6A3KDM4E | |
| SCHEMBL27721837 | 0.82 | MEN1 (0.45) | TSHRMEN1KMT2ASLC6A3KDM4E | |
| SCHEMBL20553924 | 0.82 | MEN1 (0.45) | TSHRMEN1KMT2ASLC6A3KDM4E | |
| SCHEMBL9709120 | 0.81 | HTR1A (0.43) | HTR1AHTR1DHTR2CTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049280-A | 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-17 | — | — | US | disclosed |