Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | HTR1D | P28221 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780896 | 0.88 | FAAH (0.34) | HTR1AHTR1DHTR2CTSHRHSD17B10 | |
| SCHEMBL17474254 | 0.86 | HTR1A (0.42) | HTR1AHTR1DHTR2CTSHRHSD17B10 | |
| SCHEMBL27467963 | 0.81 | HTR1A (0.40) | HTR1AHTR1DHTR2CTSHRHSD17B10 | |
| SCHEMBL2977013 | 0.79 | HSD17B10 (0.42) | HTR1AHTR1DHTR2CTSHRHSD17B10 | |
| SCHEMBL28352954 | 0.79 | HTR1A (0.42) | HTR1AHTR1DHTR2CTSHRHSD17B10 | |
| SCHEMBL3897418 | 0.79 | KDM4E (0.47) | TSHRHSD17B10POLBMAPTL3MBTL1 | |
| SCHEMBL8581956 | 0.78 | PLA2G10 (0.42) | HTR1AHTR1DHTR2CTSHRHSD17B10 | |
| SCHEMBL5006032 | 0.77 | MAPK1 (0.45) | TSHRHSD17B10KMT2ALCKPARP1 | |
| SCHEMBL10918140 | 0.77 | PKM (0.43) | HTR1AHTR1DHTR2CTSHRHSD17B10 | |
| SCHEMBL9709120 | 0.77 | HTR1A (0.43) | HTR1AHTR1DHTR2CTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049280-A | 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-17 | — | — | US | disclosed |