Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 8/20 | 0.37 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854298 | 0.78 | ERN1 (0.35) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL738274 | 0.77 | HDAC8 (0.41) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL622637 | 0.77 | CDK5 (0.47) | ALDH1A1KDM4EGAAGLADYRK1B | |
| Methane SCHEMBL28258537 | 0.76 | CDK5 (0.46) | ALDH1A1KDM4EGAAGLADYRK1B | |
| SCHEMBL2005235 | 0.75 | ALDH1A1 (0.39) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL2009640 | 0.75 | NPC1 (0.57) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL2012058 | 0.75 | ALDH1A1 (0.53) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL6156262 | 0.74 | KMT2A (0.33) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL7087038 | 0.72 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL5674897 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120116027-A1 | PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS | NOVO NORDISK A/S (DK) | 2012-05-10 | — | — | US | claimed |
| CN-102216325-A | Method for purifying human growth hormone polypeptides using affinity resins comprising specific ligands | NOVO NORDISK AS | 2011-10-12 | — | — | CN | claimed |
| EP-2356141-A1 | PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS | Novo Nordisk A/S (DK) | 2011-08-17 | — | — | EP | claimed |
| WO-2010055135-A1 | PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS | NOVO NORDISK A/S (DK) | 2010-05-20 | — | — | WO | claimed |
| US-4413999-A | CHROMATOGRAPHY, BIOCHEMICAL IMMOBILIZATION, FIBER REACTIVE DYES | RESEARCH PRODUCTS REHOVOT LTD. (IL) | 1983-11-08 | — | — | US | claimed |
| CN-106458934-B | Quinoxaline compounds and application thereof | 米伦纽姆医药公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-107245056-A | Chemical entities, composition and method | 润新生物公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-103764140-B | Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases | 韩国化学研究院 | 2017-05-17 | — | — | CN | disclosed |
| CN-106458934-A | Quinoxaline compounds and uses thereof | 米伦纽姆医药公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-2440517-B1 | CYCLOALKYLCARBAMATE BENZAMIDE ANILINE HDAC INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2014-03-26 | — | — | EP | disclosed |
| US-8394974-B2 | Process for producing optically active chromene oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-12 | — | — | US | disclosed |
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| WO-2005090357-A1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-29 | — | — | WO | disclosed |
| CN-1104227-A | Reactive dyes, their preparation and their use | CIBA GEIGY AG (CH) | 1995-06-28 | — | — | CN | disclosed |
| CN-1087694-A | Use anionic textile dyes, on modified fiber materials, make the method for product dyed thereby with the ink jet printing technique | HOECHST AG (DE) | 1994-06-08 | — | — | CN | disclosed |
| CN-1005738-B | Printing method for cellulose fabric | 西巴·盖尔基股份公司 | 1989-11-08 | — | — | CN | disclosed |
| US-4757137-A | Orthotrifluoromethyl containing phenylazonaphthol dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| CN-85107872-A | The printing method of cellulose fibre (fabric) | — | 1986-07-09 | — | — | CN | disclosed |
| EP-0135630-A1 | Amidoxime derivatives, processes for the preparation thereof and uses therefor | RESEARCH PRODUCTS REHOVOT LTD. (IL) | 1985-04-03 | — | — | EP | disclosed |
| US-4413999-A | CHROMATOGRAPHY, BIOCHEMICAL IMMOBILIZATION, FIBER REACTIVE DYES | RESEARCH PRODUCTS REHOVOT LTD. (IL) | 1983-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116027-A1 | PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS | GHRHR, GHITM, GHSR | KMT2A 3404/4885MEN1 1365/4885MAPT 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.