Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28927449 | 0.82 | CA1 (0.42) | BCL9CTNNB1PTGS2CA1CA2 | |
| SCHEMBL3294113 | 0.78 | ALDH1A1 (0.43) | CA1CA2ACHEALDH1A1CYP3A4 | |
| SCHEMBL28853177 | 0.77 | BCL9 (0.49) | BCL9CTNNB1PTGS2CA1CA2 | |
| SCHEMBL18934306 | 0.75 | PTGS2 (0.47) | BCL9CTNNB1PTGS2CA1CA2 | |
| SCHEMBL655939 | 0.73 | PPARG (0.57) | BCL9CTNNB1ALDH1A1MAPTCRHBP | |
| SCHEMBL4755048 | 0.73 | BCL9 (0.46) | BCL9CTNNB1PTGS2CA1CA2 | |
| SCHEMBL10478404 | 0.73 | CA1 (0.46) | PTGS2CA1CA2ALDH1A1CYP3A4 | |
| SCHEMBL7339889 | 0.73 | HSPB1 (0.43) | BCL9CTNNB1PTGS2CA1CA2 | |
| SCHEMBL11307407 | 0.73 | HSD17B10 (0.43) | BCL9CTNNB1PTGS2CA1CA2 | |
| SCHEMBL13195656 | 0.73 | PTGS2 (0.41) | BCL9CTNNB1PTGS2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009649-A1 | METHOD FOR PREPARING 2-(n-BUTYL)-5-NITROBENZOFURAN | FINORGA | 2011-01-13 | — | — | US | claimed |
| EP-2144866-A1 | METHOD FOR PREPARING 2-(N-BUTYL)-5-NITROBENZOFURAN | Finorga (FR) | 2010-01-20 | — | — | EP | claimed |
| WO-2008139056-A1 | METHOD FOR PREPARING 2-(N-BUTYL)-5-NITROBENZOFURAN | FINORGA (FR) | 2008-11-20 | — | — | WO | claimed |
| US-20110009649-A1 | METHOD FOR PREPARING 2-(n-BUTYL)-5-NITROBENZOFURAN | FINORGA | 2011-01-13 | — | — | US | disclosed |
| US-20110009649-A1 | METHOD FOR PREPARING 2-(n-BUTYL)-5-NITROBENZOFURAN | FINORGA | 2011-01-13 | — | — | US | disclosed |
| US-20110009649-A1 | METHOD FOR PREPARING 2-(n-BUTYL)-5-NITROBENZOFURAN | FINORGA | 2011-01-13 | — | — | US | disclosed |
| WO-2008139056-A1 | METHOD FOR PREPARING 2-(N-BUTYL)-5-NITROBENZOFURAN | FINORGA (FR) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009649-A1 | METHOD FOR PREPARING 2-(n-BUTYL)-5-NITROBENZOFURAN | CYP8B1, NISCH, CBR3 | BCL9 1781/4885CTNNB1 1891/4885PTGS2 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.