Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL9783666 | 0.85 | CYP19A1 (0.41) | HRH1HTR2ACYP19A1ALDH1A1FKBP5 | |
| Imidazole SCHEMBL9783956 | 0.83 | ALDH1A1 (0.46) | HRH1HTR2ACYP19A1ALDH1A1FKBP5 | |
| Imidazole SCHEMBL5594401 | 0.77 | SLC6A2 (0.58) | CYP19A1ALDH1A1FKBP5SLC6A2SLC6A4 | |
| Imidazole SCHEMBL9783730 | 0.77 | ALDH1A1 (0.36) | CYP19A1ALDH1A1FKBP5SLC6A2SLC6A4 | |
| Imidazole SCHEMBL9783935 | 0.76 | ALDH1A1 (0.50) | CYP19A1ALDH1A1FKBP5SLC6A2SLC6A4 | |
| SCHEMBL6661940 | 0.72 | HRH1 (0.61) | HRH1HTR2ACYP19A1TBXAS1SIGMAR1 | |
| Imidazole SCHEMBL9676326 | 0.70 | ALDH1A1 (0.56) | ALDH1A1FKBP5SLC6A2SLC6A4SLC6A3 | |
| Biphenyl SCHEMBL27756385 | 0.69 | ALDH1A1 (0.62) | CYP19A1ALDH1A1FKBP5SLC6A2SLC6A4 | |
| Biphenyl SCHEMBL986473 | 0.69 | ALDH1A1 (0.62) | CYP19A1ALDH1A1FKBP5SLC6A2SLC6A4 | |
| Benzene SCHEMBL5088215 | 0.69 | ALDH1A1 (0.87) | ALDH1A1FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |