Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783064 | 0.87 | P2RX7 (0.38) | P2RX7CYP19A1CYP3A4IDO1TP53 | |
| SCHEMBL9783926 | 0.79 | P2RX7 (0.42) | P2RX7HSD11B1CYP19A1CYP3A4IDO1 | |
| SCHEMBL9783595 | 0.75 | P2RX7 (0.39) | P2RX7CYP19A1CYP3A4IDO1MEN1 | |
| SCHEMBL9783230 | 0.75 | ALOX15 (0.38) | P2RX7HSD11B1CYP3A4IDO1MEN1 | |
| SCHEMBL9783412 | 0.74 | P2RX7 (0.40) | P2RX7CYP19A1CYP3A4IDO1MEN1 | |
| SCHEMBL9783945 | 0.69 | CYP19A1 (0.43) | P2RX7CYP19A1CYP3A4IDO1MEN1 | |
| SCHEMBL9783969 | 0.69 | P2RX7 (0.40) | P2RX7HSD11B1CYP3A4IDO1MEN1 | |
| SCHEMBL9783072 | 0.69 | IDO1 (0.39) | P2RX7CYP19A1CYP3A4IDO1TP53 | |
| SCHEMBL9783128 | 0.68 | PDE4A (0.35) | P2RX7HSD11B1CYP19A1CYP3A4IDO1 | |
| SCHEMBL11776416 | 0.68 | P2RX7 (0.45) | P2RX7CYP19A1CYP3A4IDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |