Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 4/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783983 | 0.87 | ALDH1A1 (0.39) | CYP19A1P2RX7CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9783926 | 0.78 | P2RX7 (0.42) | CYP19A1P2RX7CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9783072 | 0.78 | IDO1 (0.39) | CYP19A1P2RX7CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9783833 | 0.76 | HSD11B1 (0.33) | CYP19A1P2RX7MEN1LMNAKMT2A | |
| SCHEMBL9783064 | 0.75 | P2RX7 (0.38) | CYP19A1P2RX7CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9783505 | 0.75 | CYP19A1 (0.46) | CYP19A1P2RX7CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9783595 | 0.74 | P2RX7 (0.39) | CYP19A1P2RX7CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9783963 | 0.72 | CYP19A1 (0.38) | CYP19A1P2RX7CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL11776416 | 0.72 | P2RX7 (0.45) | CYP19A1P2RX7CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9783371 | 0.71 | CYP3A4 (0.42) | CYP19A1CYP3A4MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |