Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492587 | 0.85 | DHODH (0.39) | DHODHEPHX2CRACR2ACYP17A1KMT2A | |
| SCHEMBL8887759 | 0.82 | DHODH (0.35) | DHODHEPHX2CRACR2ASMN1; SMN2 | |
| SCHEMBL27809355 | 0.81 | DRD2 (0.30) | — | |
| SCHEMBL6912863 | 0.80 | CACNA1B (0.42) | DHODHCRACR2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8491101 | 0.78 | DHODH (0.37) | DHODHEPHX2CRACR2ANAMPTPDE2A | |
| SCHEMBL8391502 | 0.78 | DHODH (0.39) | DHODHEPHX2CRACR2ANPC1GMNN | |
| SCHEMBL977770 | 0.78 | TAS1R3 (0.37) | DHODHEPHX2CRACR2ANPC1GMNN | |
| SCHEMBL8752730 | 0.77 | DHODH (0.39) | DHODHEPHX2CRACR2AKMT2ACACNA1B | |
| SCHEMBL8492277 | 0.77 | DHODH (0.35) | DHODHEPHX2CRACR2ANAMPTPDE2A | |
| SCHEMBL9115632 | 0.77 | DHODH (0.35) | DHODHEPHX2CRACR2ANAMPTPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188009-B2 | 4-(3-aminobenzoyl)-5-cyclopropylisoxazoles effective as herbicides | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| EP-2260027-B1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-06-29 | — | — | EP | disclosed |
| US-20110015073-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-01-20 | — | — | US | disclosed |
| EP-2260027-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | Bayer CropScience AG (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009118125-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2009-10-01 | — | — | WO | disclosed |
| EP-2105437-A1 | 4-(3-Aminobenzoyl)-5-cyclopropylisoxazols as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2009-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015073-A1 | 4-(3-AMINOBENZOYL)-5-CYCLOPROPYLISOXAZOLES EFFECTIVE AS HERBICIDES | CYP4X1, PRDX4, PRDX5 | DHODH 1670/4885EPHX2 474/4885CRACR2A 4477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.