Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.40 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783946 | 0.84 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1CYP17A1HMOX2 | |
| SCHEMBL179249 | 0.74 | — | — | |
| SCHEMBL9783624 | 0.74 | CYP19A1 (0.58) | CYP11B1CYP11B2CYP19A1HMOX2CYP3A4 | |
| SCHEMBL9783931 | 0.73 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP19A1CYP17A1MEN1 | |
| SCHEMBL9783869 | 0.73 | CYP11B1 (0.46) | CYP11B1CYP11B2CYP19A1CYP17A1MEN1 | |
| Hydrochloric Acid SCHEMBL29201345 | 0.72 | NFKB1 (0.48) | CYP11B1CYP11B2CYP19A1CYP17A1MEN1 | |
| Iodide SCHEMBL29201349 | 0.72 | NFKB1 (0.48) | CYP11B1CYP11B2CYP19A1CYP17A1MEN1 | |
| Bromide SCHEMBL28416620 | 0.72 | NFKB1 (0.48) | CYP11B1CYP11B2CYP19A1CYP17A1MEN1 | |
| SCHEMBL26111774 | 0.72 | NFKB1 (0.48) | CYP11B1CYP11B2CYP19A1CYP17A1MEN1 | |
| Methane SCHEMBL27732895 | 0.72 | NFKB1 (0.48) | CYP11B1CYP11B2CYP19A1CYP17A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |