Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975250 | 0.86 | MAPT (0.53) | TDP1L3MBTL1PYGLSMN1; SMN2MAPT | |
| SCHEMBL976426 | 0.86 | PYGM (0.59) | PYGLPYGM | |
| SCHEMBL975483 | 0.83 | PYGM (0.56) | TDP1L3MBTL1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL15464521 | 0.79 | CYP1A2 (0.50) | TDP1L3MBTL1PYGLCACNA1HF10 | |
| SCHEMBL3662131 | 0.76 | CTNNB1 (0.44) | — | |
| SCHEMBL5935096 | 0.76 | PARP10 (0.63) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4846609 | 0.75 | CTNNB1 (0.58) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL27943418 | 0.74 | MAPT (0.67) | TDP1L3MBTL1RAB9ACACNA1HADRA2C | |
| SCHEMBL3265708 | 0.73 | BCAT2 (0.63) | TDP1L3MBTL1RAB9AMAPTCYP2C19 | |
| SCHEMBL29757946 | 0.73 | ADRA2C (0.71) | TDP1L3MBTL1RAB9AADRA2CSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021771-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021771-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC11, HDAC3 | TDP1 656/4885L3MBTL1 610/4885RAB9A 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.