Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952261 | 0.86 | AGXT (0.62) | AGXTHSP90AA1HSP90AB1ENPP2ALDH1A1 | |
| SCHEMBL3393935 | 0.82 | AGXT (0.40) | AGXTHSP90AA1HSP90AB1ALDH1A1LMNA | |
| SCHEMBL2110182 | 0.80 | AGXT (0.36) | AGXTALDH1A1LMNAHSD17B10LNPEP | |
| SCHEMBL3392712 | 0.78 | CA2 (0.38) | AGXTHSP90AA1HSP90AB1ALDH1A1LMNA | |
| SCHEMBL8195868 | 0.78 | HSP90AA1 (0.39) | AGXTHSP90AA1HSP90AB1ALDH1A1LMNA | |
| SCHEMBL3395441 | 0.78 | AGXT (0.37) | AGXTHSP90AA1HSP90AB1ALDH1A1LMNA | |
| SCHEMBL3799771 | 0.78 | MEN1 (0.36) | AGXTALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL8910240 | 0.77 | AGXT (0.49) | AGXTHSP90AA1HSP90AB1ENPP2ALDH1A1 | |
| SCHEMBL713329 | 0.76 | AGXT (0.36) | AGXTLNPEP | |
| SCHEMBL2111401 | 0.76 | AGXT (0.45) | AGXTHSP90AA1HSP90AB1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981861-A | ANTIULCER | HOFFMANN-LA ROCHE INC. (US) | 1991-01-01 | — | — | US | disclosed |
| US-4634710-A | ANTIULCER, ANTISECRETORY | HOFFMANN-LA ROCHE INC. (US) | 1987-01-06 | — | — | US | disclosed |