Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDXK | O00764 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393935 | 0.81 | AGXT (0.40) | MEN1KMT2AAGXTALDH1A1LMNA | |
| SCHEMBL2110182 | 0.79 | AGXT (0.36) | MEN1KMT2AAGXTALDH1A1LMNA | |
| SCHEMBL9784656 | 0.78 | AGXT (0.45) | MEN1KMT2AAGXTALDH1A1LMNA | |
| SCHEMBL8195868 | 0.77 | HSP90AA1 (0.39) | MEN1KMT2AAGXTALDH1A1LMNA | |
| SCHEMBL3395441 | 0.77 | AGXT (0.37) | MEN1KMT2AAGXTALDH1A1LMNA | |
| SCHEMBL3392712 | 0.77 | CA2 (0.38) | MEN1KMT2AAGXTALDH1A1LMNA | |
| SCHEMBL7952261 | 0.76 | AGXT (0.62) | MEN1KMT2AAGXTALDH1A1HSD17B10 | |
| SCHEMBL3395997 | 0.75 | HSP90AA1 (0.39) | MEN1KMT2AAGXTALDH1A1LMNA | |
| SCHEMBL6950031 | 0.72 | HSP90AA1 (0.41) | MEN1KMT2AAGXTALDH1A1LMNA | |
| SCHEMBL2111929 | 0.72 | ALDH1A1 (0.37) | MEN1KMT2AAGXTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |