Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | BLM | P54132 | 3/20 | 0.63 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 2/20 | 0.37 |
| ▸ | THPO | P40225 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL14741933 | 0.94 | LMNA (0.63) | LMNABLMSLC6A6CYP2C19APP | |
| SCHEMBL28703540 | 0.91 | LMNA (0.58) | LMNABLMSLC6A6CYP2C19APP | |
| Taurine SCHEMBL7213501 | 0.88 | LMNA (0.82) | LMNABLMSLC6A6CYP2C19APP | |
| Taurine SCHEMBL1826395 | 0.88 | LMNA (0.82) | LMNABLMSLC6A6CYP2C19APP | |
| SCHEMBL827 | 0.87 | — | — | |
| SCHEMBL249947 | 0.87 | LMNA (0.50) | LMNABLMSLC6A6CYP2C19APP | |
| SCHEMBL31042640 | 0.87 | APP (0.64) | LMNABLMSLC6A6CYP2C19APP | |
| Propylamine SCHEMBL14742197 | 0.87 | LMNA (0.55) | LMNABLMSLC6A6CYP2C19APP | |
| SCHEMBL28941671 | 0.86 | LMNA (0.52) | LMNABLMSLC6A6CYP2C19APP | |
| Taurine SCHEMBL27709203 | 0.86 | LMNA (0.78) | LMNABLMSLC6A6CYP2C19APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013307-A1 | PERSONAL CARE ARTICLES | The Procter & Gamble Company (US) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014210230-A1 | PERSONAL CARE ARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 2014-12-31 | — | — | WO | disclosed |
| WO-2013033046-A2 | FLUORESCENT PL MARKERS FOR ISOELECTRIC FOCUSING SEPARATIONS AND FLUORESCENT LABELING | VIGH GYULA (US) | 2013-03-07 | — | — | WO | disclosed |
| CN-101466819-A | Process for preparing acylalkylisethionate ester compositions and process for producing same | HUNTSMAN SPEC CHEM CORP (US) | 2009-06-24 | — | — | CN | disclosed |
| US-5007955-A | Applying quaternary ammonium sulfonates to weeds | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1991-04-16 | — | — | US | disclosed |