Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436338 | 0.84 | TSHR (0.50) | ALDH1A1HTTTSHRLMNA | |
| SCHEMBL10500278 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4ETDP1MAPTGAA | |
| SCHEMBL23555133 | 0.77 | SLC6A2 (0.50) | ALDH1A1SLC6A2SLC6A4KDM4ETDP1 | |
| SCHEMBL4703338 | 0.76 | NOTUM (0.50) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL5228101 | 0.75 | MEN1 (0.55) | ALDH1A1SLC6A2SLC6A4KDM4ETDP1 | |
| SCHEMBL30852175 | 0.74 | FFAR1 (0.44) | C5AR1FFAR4 | |
| SCHEMBL11457763 | 0.73 | KMT2A (0.46) | ALDH1A1SLC6A2SLC6A4KDM4ETDP1 | |
| SCHEMBL1688137 | 0.73 | SLC6A2 (0.44) | ALDH1A1SLC6A2SLC6A4KDM4ETDP1 | |
| SCHEMBL2558839 | 0.72 | NPC1 (0.49) | ALDH1A1KDM4ETDP1MAPTGAA | |
| SCHEMBL2557270 | 0.72 | ALDH1A1 (0.59) | ALDH1A1KDM4ETDP1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025013-A | Antiarrhythmia or antifibrillatory agents | RHONE-POULENC SANTE (FR) | 1991-06-18 | — | — | US | disclosed |